Ricardo Castro Selected Research

Hyperlactatemia

12/2017	A hypoperfusion context may aid to interpret hyperlactatemia in sepsis-3 septic shock patients: a proof-of-concept study.
1/2017	Capillary refill time during fluid resuscitation in patients with sepsis-related hyperlactatemia at the emergency department is related to mortality.
1/2016	Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
8/2013	Severe abnormalities in microvascular perfused vessel density are associated to organ dysfunctions and mortality and can be predicted by hyperlactatemia and norepinephrine requirements in septic shock patients.
8/2013	Effects of dobutamine on systemic, regional and microcirculatory perfusion parameters in septic shock: a randomized, placebo-controlled, double-blind, crossover study.
10/2012	Relationship of systemic, hepatosplanchnic, and microcirculatory perfusion parameters with 6-hour lactate clearance in hyperdynamic septic shock patients: an acute, clinical-physiological, pilot study.
1/2012	Persistent Sepsis-Induced Hypotension without Hyperlactatemia: A Distinct Clinical and Physiological Profile within the Spectrum of Septic Shock.
8/2011	Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock?

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Ricardo Castro Research Topics

Disease

23	Septic Shock (Toxic Shock Syndrome) 02/2022 - 05/2006
9	Shock 02/2022 - 08/2016
8	Hyperlactatemia 12/2017 - 08/2011
5	COVID-19 11/2021 - 01/2021
5	Sepsis (Septicemia) 01/2017 - 08/2011
3	Infections 06/2021 - 03/2020
2	Respiratory Insufficiency (Respiratory Failure) 10/2021 - 01/2021
2	Critical Illness (Critically Ill) 01/2021 - 01/2009
2	Hypoxia (Hypoxemia) 11/2020 - 06/2020
2	Hypotension (Low Blood Pressure) 01/2016 - 05/2006
2	Thrombosis (Thrombus) 03/2012 - 01/2012
1	Acne Vulgaris 06/2021
1	Psoriasis (Pustulosis Palmaris et Plantaris) 06/2021
1	Alopecia (Baldness) 06/2021
1	Inflammation (Inflammations) 01/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 03/2020
1	Myocarditis (Carditis) 03/2020
1	Cardiomyopathies (Cardiomyopathy) 03/2020
1	Bronchiectasis 03/2019
1	Heart Failure 01/2019
1	Soft Tissue Infections 09/2018
1	Sialadenitis 12/2015
1	Thyroid Neoplasms (Thyroid Cancer) 12/2015
1	Low Cardiac Output 08/2013
1	Heart Arrest (Cardiac Arrest) 07/2012
1	Lung Injury 03/2012
1	Pulmonary Embolism 03/2012
1	Embolism (Embolus) 03/2012
1	Intra-Abdominal Hypertension 12/2008
1	Lactic Acidosis 05/2006
1	Osteoarthritis 01/2002

Drug/Important Bio-Agent (IBA)

12	Lactic Acid (Lactate)FDA LinkGeneric 11/2020 - 08/2011
2	Biomarkers (Surrogate Marker)IBA 06/2020 - 03/2012
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 08/2013 - 05/2006
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 10/2021
1	Liposomes (Liposome)IBA 06/2021
1	InflammasomesIBA 01/2021
1	AlbuminsIBA 01/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	Interleukin-18 (Interleukin 18)IBA 01/2021
1	Pyruvic Acid (Pyruvate)IBA 06/2020
1	Methicillin (Metin)FDA Link 03/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 03/2020
1	trans-crotonin (CTN)IBA 03/2020
1	Heterophile AntibodiesIBA 03/2020
1	TroponinIBA 03/2020
1	imidazoleIBA 09/2018
1	Ionic LiquidsIBA 09/2018
1	CarbonIBA 09/2018
1	Protein CIBA 12/2016
1	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2016
1	Hydrocortisone (Cortisol)FDA LinkGeneric 08/2016
1	Dexmedetomidine FDA Link 01/2016
1	EndotoxinsIBA 01/2016
1	esmolol (Brevibloc)FDA LinkGeneric 01/2016
1	Adrenergic Agents (Adrenergic Drugs)IBA 01/2016
1	SteroidsIBA 12/2015
1	Dobutamine FDA LinkGeneric 08/2013
1	pro-brain natriuretic peptide (1-76)IBA 03/2012
1	Brain Natriuretic Peptide (Natrecor)FDA Link 03/2012
1	Adenosine (Adenocard)FDA LinkGeneric 01/2012
1	CreatinineIBA 12/2008
1	EtoricoxibIBA 01/2002
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2002

Therapy/Procedure

22	Resuscitation 02/2022 - 01/2009
4	Length of Stay 01/2022 - 03/2019
3	Therapeutics 02/2022 - 12/2015
2	Artificial Respiration (Mechanical Ventilation) 10/2021 - 01/2021
2	Early Goal-Directed Therapy 07/2018 - 04/2018
2	Controlled Hypotension 01/2012 - 08/2011
1	Cannula 11/2021
1	Urinary Catheters 03/2020
1	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 01/2019
1	Radiotherapy 12/2015
1	Catheters 03/2012
1	Hemofiltration 05/2006
1	Salvage Therapy 05/2006